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In the 1920s, Edward Bernays - the father of modern public relations - helped the American Tobacco Company market cigarettes to women by hiring female activists and marchers to smoke during New York's Easter Day Parade and present cigarettes as "torches of freedom" in the first years of women's suffrage

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(PMC) d) Genetic, enzymatic and immunologic differences Variations in genes (including those affecting CYP enzymes), immune system differences and differential susceptibility to oxidative stress may contribute to sex differences in disease risk after tobacco exposure